Palliative Radiation Therapy for Head and Neck Cancers

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Radiation therapy for head and neck cancers.

A general review of the therapeutic experience of the management of carcinoma of the head and neck at the Massachusetts General Hospital and Massachusetts Eye and Ear Infirmary is presented. Early lesions are highly curable by radiation therapy alone; the advanced lesions are preferably treated by combined irradiation and surgery, with improved survival rates. Concepts of various approaches are...

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Gene therapy for head and neck cancers.

Despite advances in surgery, radiotherapy, and chemotherapy, survival of patients with squamous cell carcinoma of the head and neck has not significantly improved over the past 30 years. Locally recurrent or refractory disease is particularly difficult to treat. Repeat surgical resection and/or radiotherapy are often not possible, and long-term results for salvage chemotherapy are poor. Recent ...

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[Radiation therapy for head and neck cancer].

Radiation therapy is the first choice of treatment for most of the early squamous cell carcinoma of the head and neck. Conventional radiotherapy however, contributes to the high local control rates only for carcinoma of the glottic larynx and the nasopharynx. Squamous cell carcinoma of the other sites cannot be sterilized easily only by external beam radiation therapy alone. Chemoradiotherapy, ...

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Biological Basis for Increased Sensitivity to Radiation Therapy in HPV-Positive Head and Neck Cancers

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Commentary (Frank): Gene Therapy for Head and Neck Cancers

Lamont et al have presented a very clear and concise review of current gene therapy strategies in the management of squamous cell carcinoma of the head and neck. While the presentation highlighted the most important work to date in this expanding field, it also made reference to some controversies and challenges that we are now facing. With this in mind, I would like to expand on and clarify se...

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ژورنال

عنوان ژورنال: International Journal of Radiation Oncology*Biology*Physics

سال: 2019

ISSN: 0360-3016

DOI: 10.1016/j.ijrobp.2019.05.024